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Hi doctors,i have aphte in mouth only from i was a child,i tried all kinds of medicine but in vain.they go and back again all the time of years.plz what should i do?
Apr 22, 2013

Dr. Zakia Dimassi Pediatrics
Recurrent aphthous ulcers is not related to any kind of infection (viral, bacterial or fungal) according to medical research. The most valid explanation is that of immune system malfunction, whereby the immune system, whose normal function is to protect the body against invading organisms, gets confused and actually starts attacking the tissues of the body itself. The exact triggers of this unusual reaction are not known, although some patients can relate the onset of the lesions to such things as stress, minor injury to the lining of the mouth, or the menstrual cycle in females.
Predisposing factors include: anemia (due to iron, folic acid, or Vit B12 deficiency), absorption disorders in the gut (like gluten sensitivity or celiac disease, Crohn's disease ...), and certain drugs (anti-inflammatory drugs manily).
A special group includes: Major aphthous ulcerations where you get much larger sores than usual that are almost always present in the mouth;
Herpetiform ulcerations: you get numerous very small aphthous ulcerations that clinically resemble a herpes infection; Behcet's disease, a rare condition in which patients not develop mouth sores that are identical to recurrent aphthous ulcerations, in addition eye problems and similar sores in the genital area.
A few blood tests may help to rule out any underlying conditions like anemia or Behcet's disease, which, once treated, the ulcers should improve. If these these conditions don't exist, then the mainstay of treatment is topical steroids, in addition to mouth wash (chlorhexidine).
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Dr. Salim Saab Otolaryngology (ENT)
a simple aphtous ulcer improves with sodium bicarbonate recurrent needs colchicine we nbbd to know if there is an underlying disease
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