Siofor is not insulin- it's metformin. It acts by decreasing blood sugar level by decreasing sugar production from the liver; it may also decrease sugar absorption in the es and increase response to insulin, hence aiding in weight loss. Use for enhancing weight loss is a known off-label use (that is, not the original use of this medication), and is usually used in women who have polycystic ovary syndrome (they have cysts on their ovaries along with menstrual irregularities, obesity, and excess hair). It is effective but must not be used if you have kidney problems (because it's cleared in the kidneys). The main side effects are diarrhea, nausea, vomiting, and flatulence.
You need to make kidney function test prior to initiation of therapy and then at least once per year while you're on metformin.
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It's recommended by the American Cancer Association that every adult between the age of 20 and 80 does an annual skin screening by a licensed dermatologist.
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