Fatigue and body aches in the setting of a depressed mood are generally psychological in origin. You do have to be examined though to make sure there are no physical illnesses. There are many medicines that can make you feel better, medicines that should be prescribed by your family physician or psychiatrist. Sometimes just speaking with a professional would do you great.
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It is recommended that all individuals see a Family Doctor for a full medical examination annually. Adults should get their blood pressure checked (US Preventive Task Force), a flu vaccine (CDC) and more each year.