To be able to tell how effectively different drugs (Volfast= ddiclofenac) work in treating an ailment, we resort to “Evidence-based medicine”, whereby the drug in question is compared to placebo (or no treatment) in clinical trials where the people running the trial don't know which patients received the drug vs those who received placebo.
Researchers from the Cochrane Collaboration systematically evaluated these kinds of trials on diclofenac. They addressed the following questions: How effectively does diclofenac relieve pain? And how effectively can it relieve other symptoms associated with migraine, such as nausea, vomiting or sensitivity to light and sound? They concluded that Diclofenac relieves headaches better than placebo, partly or completely after a short time with a 50 mg dose. Nausea, vomiting and sensitivity to light and sound also probably get better. But only a few trials looked into this question.
Diclofenac seems to have a similar effectiveness as other drugs from the group of non-steroidal anti-inflammatory drugs like ibuprofen. But only a few trials compared the drugs directly with one another, so there might be minor differences.
Diclofenac can can increase the risk of bleeding, particularly if taken regularly. It can also cause stomach ulcers, particularly in people who are prone to this problem. So better avoided if you have bleeding tendency, are on blood thinners, or have a stomach ulcer. If you have a sensitive stomach use a proton pump inhibitor in parallel (like gastrimut or Nexium).
And remember: migraine therapy is case-specificy. What might work for 1 patient might not work for another. If your migraine is not responding to advil and profenid, the chances that it would respond to diclofenac are slim. You most probably need to be maintained on regular therapy (with sumatriptans or a beta blocker) in pain free periods, and reserve drugs like diclofenac or advil for acute attacks. See a neurologist to get optimal treatment.
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