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24 years
Sexual dysfunction caused by zoloft and b blocker is reversible?
Aug 22, 2014

Dr. Zakia Dimassi Pediatrics
Paroxetine, an antidepressant from the family of selective serotonin reuptake inhibitors (SSRIs), has been found to bind to serotonin transporters by interacting with the sulfhydryl group. This has lead to the hypothesis that SSRIs could cause deleterious effects on spermatozoa (sperm cells), because binding to sulfhydryl groups of sperm membrane is associated with spermicidal (killing of sperm cells) action. Published data clearly shows that chronic SSRI treatment has a detrimental effect on spermatogenesis (synthesis of sperm), impedes sperm transportation, damages the sperm cell membrane, alters sperm DNA and/or effects hormonal homeostasis.
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