Familial Mediterranean fever is a disorder usually passed down through families (inherited), which involves repeated fevers and inflammation that often affects the lining of the abdomen, chest, or joints
Symptoms usually begin between ages 5 and 15 years. Inflammation in the lining of the abdominal cavity, chest cavity, skin, or joints occurs, along with high fevers that usually peak in 12 to 24 hours. Attacks may vary in severity of symptoms. Patients are usually symptom-free between attacks.
Symptoms may include repeated episodes of:
•Abdominal pain
•Chest pain that is sharp and gets worse when taking a breath
•Fever or alternating chills and fever
•joint pain
•Skin lesions that are red and swollen and range from 5 - 20 cm in diameter
There is no specific test to diagnose this disease. If genetic testing shows you have the mutation known to be associated with this condition, and your symptoms match a typical pattern, the diagnosis is nearly certain.
Certain blood tests may be higher than normal when done during an attack. like Complete blood count (CBC) that may show elevated While blood cell count, elevated C-reactive protein or Erythrocyte sedimentation rate (ESR)
and the Fibrinogen test
The goal of treatment for familial Mediterranean fever is to control symptoms. Colchicine, a medicine that reduces inflammation, may help during an attack and may prevent further attacks. It can also help prevent a serious complication called systemic amyloidosis; a condition in which abnormal proteins build up in the organs and joints and affects their function.
There is no known cure for familial Mediterranean fever. Most people continue to have attacks, but the number and severity of attacks is different from person to person.
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It's recommended by the American Cancer Association that every adult between the age of 20 and 80 does an annual skin screening by a licensed dermatologist.
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