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23 years
Is it normal to feel a bit of burning sensation on my face during my 4th month of Isosupra? I increased the dosage in the beginning of this month.
May 24, 2013

Dr. Zakia Dimassi Pediatrics
Burning sensation could be secondary to skin dryness which a common side effect of isotretinoin (the active component in Isosupra) treatment, so you should apply a good moisturizer cream (something like Lipikar -LaRoche Posay), but if this is accompanied by swelling of your face, lips, tongue, or throat, +/- difficulty breathing and hives, these indicate a severe allergic reaction and you then you must seek medical advice on an emergency basis.

Stop using isotretinoin and call your doctor at once if you have any of these serious side effects:
1. depressed mood, trouble concentrating, sleep problems, crying spells, aggression or agitation, changes in behavior, hallucinations, thoughts of suicide or hurting yourself;
2. sudden numbness or weakness, especially on one side of the body;
3. blurred vision, sudden and severe headache or pain behind your eyes, sometimes with vomiting;
4. hearing problems, hearing loss, or ringing in your ears;
5. seizure (convulsions);
6. severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
7. loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
8. severe diarrhea, rectal bleeding, black, bloody, or tarry stools;
9. fever, chills, body aches, flu symptoms, purple spots under your skin, easy bruising or bleeding;
10. severe blistering, peeling, and red skin rash; or
11. joint stiffness, bone pain or fracture.

Less serious side effects may include:
1. joint pain, back pain;
2. feeling dizzy, drowsy, or nervous;
3. dryness of the lips, mouth, nose, or skin; or
4. cracking or peeling skin, itching, rash, changes in your fingernails or toenails.
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