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24 years
I'm taking primolut to delay my period, is it safe? Does it have side effects?
Aug 27, 2014

Dr. Zakia Dimassi Pediatrics
No medication is absolutely side-effect free; the only difference in between certain adverse effects and others is that some are quite bothersome, while others may pass unnoticed.
Concerning Primolut Nor, it is a synthetic (as opposed to naturally produced) hormone whose activity is similar to that of progesterone, the naturally produced hormone that promotes the conditions in the uterus necessary for conception. When taken on a daily basis, it inhibits the signals sent by the brain to the uterus, thereby withholding ovulation and menstrual bleeding. Upon discontinuation, bleeding occurs (withdrawal bleeding).Common side effects include abdominal discomfort (bloating), nausea/nautiousness. headache, body swelling (edema), and vaginal spotting/bleeding (known as breakthrough bleeding).
One particularly serious adverse effect is the possibility of venous thrombosis, or formation of blood clots in blood vessels. But this usually occurs more commonly in women aged 35 and above, with risk factors like:
Age (above 35 years)
Obesity (body mass index over 30 kg/m2, a positive family history (i.e. venous or arterial thromboembolism ever in a sibling or parent at a relatively early age; if a hereditary predisposition is known or suspected, referral to a specialist for advice before use is recommended)
Prolonged immobilization (such as after major surgery, or long flights)
Smoking (with heavier smoking and increasing age the risk further increases, especially in women over 35 years of age), and
-Existing diseases (high cholesterol, hypertension, migraine, and heart disease).
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