Ca 125 can get elevated when an ovarian cancer develops, but for other reasons as well, such as endometriosis or any inflammation in the pelvis. It is only a marker to interpret depending on the clinical context; so no, an elevated Ca125 isn't always a synonym of ovarian cancer.
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It is recommended that all individuals see a Family Doctor for a full medical examination annually. Adults should get their blood pressure checked (US Preventive Task Force), a flu vaccine (CDC) and more each year.
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It’s recommended by the American Academy of Ophthalmology that every adult between the ages of 18 and 80 does an eye examination at least once every two years.
It's recommended by the American Cancer Association that every adult between the age of 20 and 80 does an annual skin screening by a licensed dermatologist.
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