The pressure and friction exerted by the socks may cause hair loss in those areas. This phenomenon is also observed in people with peripheral vascular disease, whereby the blood supply to the peripheral parts of the body is suboptimal - this is associated with diabetes and peripheral artery disease.
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It is recommended that all individuals see a Family Doctor for a full medical examination annually. Adults should get their blood pressure checked (US Preventive Task Force), a flu vaccine (CDC) and more each year.