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17 years
Is there a cure for epidermodysplasia verruciformis?
Jul 21, 2014

Dr. Rania Mousa General Medicine
Epidermodysplasia verruciformis (EV) is an inherited skin disorder characterized by eruptions of wart-like lesions that may occur anywhere on the body. These lesions are caused by infection with the human papillomavirus (HPV).

Unfortunately epidermodysplasia verruciformis is a lifelong disease. Even though lesions can be treated or removed as they appear, patients with EV will continue to develop these lesions throughout life.
In many cases lesions may develop and remain unchanged for years. The greatest risk is that in 30-60% of EV patients these lesions will change into skin cancers.

Currently there is no treatment to prevent new EV lesions from occurring. The management of EV involves a combination of medical and surgical treatments alongside patient counselling and education.
treatment plan is usually by :
-using sun protection . Exposure to sunlight (UVB and UVA) has been shown to increase the rate of EV lesions turning into skin cancers
-Treat and remove warts,this includes chemical treatment, cryotherapy with liquid nitrogen and electrosurgery.
-Oral and topical treatment with retinoids (isotretinoin and acitretin), fluorouracil and imiquimod are proving to be useful agents.
So ,in coordination with the doctor ,treatment is held on periods of time .
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