Glioblastomas multiforme are the most difficult to treat and most of them relapse within the first year of treatment, while the other types are bit better .(astrocytomas,etc) .
Brain tumors , usually are a disease of the brain, infiltrating the whole brain, and what we treat usually is what we see only . as it is in the brain, most often surgeries are difficult to eradicate the whole tumors (due to sensitive areas in the brain that we can't remove (might lead to permanent neurological dammage or even death). gamma knife can be a good option to increasethe chance of radiotherapy, and we usually we give chemotherapy with radiotherapy together , then chemotherapy alone.